There is some question of what S6E1 episode title, "LA X" means. If we go back to my tangent to the Periodic Table of Elements:
La is the symbol for lanthanum, a silvery-white rare earth metal. It comes from the Greek word for ESCAPE NOTICE.
X is the symbol for TEN or in math, an independent variable.
LA X could then represent the phrase THE TENTH ESCAPE NOTICE, which could trigger a response from higher forces (They're Coming! as Jacob said).
It would tie nicely into the Hatch's warning symbols from the countdown timer which said HE ESCAPES PLACE OF DEATH.